2026 NFL Week 1 odds, betting: Full list of Week 1 spreads


The calendar has turned to September and we will finally be playing NFL games that count in a few days. One of them will take place for the very first time in Melbourne, Australia, as the Los Angeles Rams “host” the San Francisco 49ers as 3.5-point favorites.

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Here are the odds for every Week 1 NFL game at BetMGM:

Wednesday

New England Patriots at Seattle Seahawks (-3.5, 44.5)

Thursday

San Francisco 49ers at Los Angeles Rams (-3.5, 48.5) in Melbourne, Australia

Sunday

1 p.m. ET

Tampa Bay Buccaneers at Cincinnati Bengals (-4, 50.5)

Atlanta Falcons at Pittsburgh Steelers (-3, 42)

Buffalo Bills at Houston Texans (-1, 44.5)

Baltimore Ravens (-3.5, 48) at Indianapolis Colts

Cleveland Browns at Jacksonville Jaguars (-8, 40.5)

New York Jets at Tennessee Titans (-1.5, 39.5)

New Orleans Saints at Detroit Lions (-7, 50)

Chicago Bears (-3, 47.5) at Carolina Panthers

4:25 p.m. ET

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Miami Dolphins at Las Vegas Raiders (-3.5, 40.5)

Arizona Cardinals at Los Angeles Chargers (-10.5, 47)

Washington Commanders at Philadelphia Eagles (-5, 45.5)

Green Bay Packers at Minnesota Vikings (-1.5, 45.5)

8:20 p.m. ET

Dallas Cowboys (-3, 48.5) at New York Giants

Monday

Denver Broncos at Kansas City Chiefs (-2.5, 43.5)


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